Congenital heart defects (CHD) represent the most common congenital malformations globally and constitute a leading cause of neonatal mortality, with early maternal risk factors playing significant ...

Scientists at the Icahn School of Medicine at Mount Sinai and collaborators have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth defect.

Acyanotic heart disease is a type of congenital heart defect that causes abnormal blood flow. It can range from mild to severe. Babies with the condition can seem out of breath and fatigued.

Congenital heart defects are the most common form of human birth defect, but we still don't fully understand what causes them. Previous research had suggested that some heart defects could be ...

One to two out of every 100 newborn babies are born with a Congenital Heart Defect (CHD), yet the exact cause remains unclear. Human geneticists at the University Medicine Oldenburg (Germany) have now ...

Dombrowsky et al.: “DNA methylation analysis of NOTCH1 variants reveals the first episignature for nonsyndromic congenital heart defects“,Genome Medicine, 7. Januar 2026, ...

Among babies with severe congenital heart disease (CHD), neurological abnormalities tended to cluster in those who had been exposed to some placental pathology while still in the womb, a single-center ...

Early detection is key to ensuring that a care plan is in place before the baby is born, allowing for timely treatment and interventions. (Children's Hospital of Michigan.) The advertiser paid a fee ...

On World Birth Defects Day, India's congenital anomalies burden is spotlighted with roughly 472,000 affected births annually, ...

Signs of CHD may be subtle and parents tend to look away from these. However, if you spot the early signs of CHD, it can help in early treatment and also prevent it from turning fatal.

A congenital heart defect is a condition you’re born with. Types of heart defects vary in severity — with some, you’ll need surgery as a child, while others don’t need treatment until later in life or ...